About
Mesogun（U225）
Mesogun (U225), also known as a next-generation skin booster treatment, is believed to potentially provide supplementary support for pore condition, fine lines, and overall skin radiance and firmness. The micro-needling action is believed to potentially stimulate the skin's natural response, which may contribute to collagen and elastin production and provide supplementary support for skin texture and overall skin quality.
Beyond facial care, this treatment can also be applied to the scalp. Scalp treatments with Mesogun are believed to potentially provide supplementary support for concerns such as clogged pores, dryness, and scalp environment imbalance, helping to create conditions conducive to maintaining healthy hair.
Beyond facial care, this treatment can also be applied to the scalp. Scalp treatments with Mesogun are believed to potentially provide supplementary support for concerns such as clogged pores, dryness, and scalp environment imbalance, helping to create conditions conducive to maintaining healthy hair.
Mesogun（U225）'s Benefits
01
Up to 10,000 Shots in a Single Session
The Mesogun is a medical device developed in France, designed to deliver active ingredients directly into the skin.
Administering approximately 7 shots per second, a single session can achieve up to approximately 10,000 injections.
Administering approximately 7 shots per second, a single session can achieve up to approximately 10,000 injections.
02
Achieve precise, targeted skin booster injections
It is effective for improving skin texture, pores, and fine lines, and by adjusting the needle depth, injections can also be performed around the eyes.
Using ultra-fine needles, the injection speed is fast while minimizing pain.
Using ultra-fine needles, the injection speed is fast while minimizing pain.
03
Choose Your Active Ingredient
At our clinic, we offer a selection of treatment agents including PRP, iPS Cell-Derived Exosomes, and Umbilical Cord-Derived Stem Cell Secretome.
Mesogun（U225） Expected effects
Skin Quality Improvement
- Helping reduce the appearance of fine lines
- Supporting overall skin quality improvement
- Helping improve acne-prone skin
- Helping tighten and minimize pores
Hair Growth Support
- Supporting hair growth and regrowth
- Helping improve the scalp environment to support healthy hair growth
- May also be considered as a complementary option for those seeking additional scalp care following hair transplant procedures
- ※効果には個人差があります。※治療をご検討の際は、医師による十分な説明をもとにご判断ください。
Treatment Agents Offered at Ginza YR Clinic for the Mesogun (U225)
Our treatment
Our treatment
At our clinic, we offer three treatment options using the Mesogun (U225), which can be tailored to care goals.
-Vial 01
iPS Cell-Derived Exosome
This treatment uses exosomes derived from iPS cells (induced pluripotent stem cells). Believed to contain components involved in intercellular communication, it may potentially influence the condition of the skin and scalp environment. It is available for those with concerns about skin firmness and elasticity, or those looking to support their scalp condition.
-Vial 02
Umbilical Cord-Derived Stem Cell Secretome
This treatment uses a formula containing active components including EGF, ANG2, FGF2, HGF, and CD63, and may be used to provide supplementary support for concerns related to the skin and scalp environment. It is one of the available options for those interested in supporting healthy skin and scalp condition.
-Vial 03
PRP Skin Regeneration Therapy
This treatment uses PRP (Platelet-Rich Plasma) extracted from the patient's own blood, with the aim of providing supplementary support for skin condition maintenance. Believed to contain growth factors, it may be used to provide supplementary support for concerns such as dark spots, wrinkles, fine lines, and changes in skin firmness or hydration. Scalp treatments are also available, making it an option for those looking to support their scalp environment as well.
※Results vary between individuals, and the same effects or changes cannot be guaranteed for all patients. ※If you are considering this treatment, please ensure you have received a thorough explanation from a physician before making your decision.
Treatment
01
iPS Cell-Derived Exosome
Uses high-purity, highly active exosomes derived from iPS (induced pluripotent stem) cells. With superior regenerative and signaling capabilities, they strongly support the repair of skin and hair follicle cells. They help enhance skin firmness and elasticity, while also maintaining hair resilience and volume. Recommended for those seeking advanced regenerative care.
Treatment
02
Umbilical Cord-Derived Stem Cell Secretome
Formulated with enhanced levels of key active components such as EGF, ANG2, FGF2, HGF, and CD63. Some components are increased by up to eight times, with overall active ingredient levels reaching approximately ten times higher, efficiently supporting regeneration and repair. It works not only on the skin but also on the scalp, promoting a healthy skin and scalp environment.
Treatment
03
PRP Skin Regeneration Therapy
Utilizes PRP (platelet-rich plasma) extracted from the patient’s own blood to stimulate the skin’s natural regenerative ability. Growth factors promote skin repair, helping improve spots, wrinkles, and fine lines, while restoring firmness, hydration, and overall skin health. Recommended for those beginning to notice signs of aging.
Treatment
01
iPS Cell-Derived Exosome
Uses high-purity, highly active exosomes derived from iPS (induced pluripotent stem) cells. With superior regenerative and signaling capabilities, they strongly support the repair of skin and hair follicle cells. They help enhance skin firmness and elasticity, while also maintaining hair resilience and volume. Recommended for those seeking advanced regenerative care.
Treatment
02
Umbilical Cord-Derived Stem Cell Secretome
Formulated with enhanced levels of key active components such as EGF, ANG2, FGF2, HGF, and CD63. Some components are increased by up to eight times, with overall active ingredient levels reaching approximately ten times higher, efficiently supporting regeneration and repair. It works not only on the skin but also on the scalp, promoting a healthy skin and scalp environment.
Treatment
03
PRP Skin Regeneration Therapy
Utilizes PRP (platelet-rich plasma) extracted from the patient’s own blood to stimulate the skin’s natural regenerative ability. Growth factors promote skin repair, helping improve spots, wrinkles, and fine lines, while restoring firmness, hydration, and overall skin health. Recommended for those beginning to notice signs of aging.
Recommended for these concerns
You want to improve skin laxity and restore firmness and radiance
You are starting to notice fine lines or dryness
You want to tighten visibly enlarged pores
You want to improve the appearance of acne scarring
You want to support a healthier scalp environment and overall hair condition
Treatment overview
Mesogun（U225）
【Treatment Overview】
This treatment uses a French-made electronic micro-injection device (U225) to deliver beauty-enhancing ingredients evenly into the appropriate layer of the skin, at a rate of approximately 7 shots per second, with up to 10,000 shots or more in a single session. The formulas used may include PRP, exosomes, and umbilical cord secretome.
【Treatment Duration & Frequency】
Recommended once every 4 to 6 weeks, with each session taking approximately 30 minutes to 1 hour.
【Downtime】
Recovery typically occurs naturally within a few hours to about a day.
※Makeup can be applied on the same day. Bathing is permitted on the day of treatment, avoiding the treated area. However, please avoid strenuous exercise and saunas for 24 hours after treatment, and be sure to take thorough sun protection measures. Please also avoid using strongly stimulating cosmetics or receiving massages in the treated area for several days following the procedure.
【Key Risks & Side Effects】
Redness or mild swelling may occur on the day of treatment, typically resolving within a few hours to three days. Bruising may occur in rare cases, usually clearing up within about a week. Allergic reactions to the formula used may also occur.
※Results and post-treatment side effects vary between individuals.※Regarding Mesogun (U225)① The Mesogun (U225) used in this treatment is an unapproved medical device that has not received approval under Japan's Pharmaceuticals and Medical Devices Act.
② This device is obtained by our physicians through personal import (for reference, see the Ministry of Health, Labour and Welfare's guidance for individuals purchasing pharmaceutical products from overseas).
③ There are currently no approved medical devices in Japan with the same performance and intended use as this device.
④ While this device holds CE certification in Europe, its safety and efficacy have not been fully verified within Japan. The procedure may result in redness, swelling, pain, bruising, bleeding, infection, pigmentation changes, scarring, or allergic reactions at the injection site.
⑤ In the rare event of a serious adverse reaction or health impact, this treatment is not eligible for compensation under Japan's national Relief System for Adverse Drug Reactions.
※Regarding the Umbilical Cord-Derived Stem Cell Secretome
① The umbilical cord-derived stem cell secretome used in this treatment is an unapproved drug that has not received approval under Japan's Pharmaceuticals and Medical Devices Act.
② The raw material is sourced from the umbilical cord blood of healthy Japanese donors, obtained through channels intended for domestic medical institutions.
③ There are currently no approved pharmaceutical products in Japan with the same composition or properties as this treatment.
④ This product has not been approved in major Western countries, and information regarding potential significant risks has not been fully established.
⑤ In the rare event of a serious adverse reaction, this treatment is not eligible for compensation under Japan's national Relief System for Adverse Drug Reactions.
※Regarding iPS Cell-Derived Exosomes
① The iPS cell-derived exosomes used in this treatment are an unapproved drug that has not received approval under Japan's Pharmaceuticals and Medical Devices Act.
② This product is obtained through channels intended for domestic medical institutions and is used under the professional judgment of our physicians.
③ There are currently no approved pharmaceutical products in Japan with the same composition or properties as this treatment.
④ This product has not been approved in major Western countries. While research is currently being conducted in several countries, information regarding potential significant risks has not yet been fully established.
⑤ In the rare event of a serious adverse reaction, this treatment is not eligible for compensation under Japan's national Relief System for Adverse Drug Reactions.
※Regarding PRP
This treatment is provided in accordance with Japan's Act on the Safety of Regenerative Medicine (Notification Numbers: PB3250225 / PC3250242 / PC3250241).
※Regarding Autologous Adipose-Derived Stem Cells
This treatment is provided in accordance with Japan's Act on the Safety of Regenerative Medicine (Notification Numbers: PB3250224 / PB3250226 / PB3250279 / PB3250305).
② This device is obtained by our physicians through personal import (for reference, see the Ministry of Health, Labour and Welfare's guidance for individuals purchasing pharmaceutical products from overseas).
③ There are currently no approved medical devices in Japan with the same performance and intended use as this device.
④ While this device holds CE certification in Europe, its safety and efficacy have not been fully verified within Japan. The procedure may result in redness, swelling, pain, bruising, bleeding, infection, pigmentation changes, scarring, or allergic reactions at the injection site.
⑤ In the rare event of a serious adverse reaction or health impact, this treatment is not eligible for compensation under Japan's national Relief System for Adverse Drug Reactions.
※Regarding the Umbilical Cord-Derived Stem Cell Secretome
① The umbilical cord-derived stem cell secretome used in this treatment is an unapproved drug that has not received approval under Japan's Pharmaceuticals and Medical Devices Act.
② The raw material is sourced from the umbilical cord blood of healthy Japanese donors, obtained through channels intended for domestic medical institutions.
③ There are currently no approved pharmaceutical products in Japan with the same composition or properties as this treatment.
④ This product has not been approved in major Western countries, and information regarding potential significant risks has not been fully established.
⑤ In the rare event of a serious adverse reaction, this treatment is not eligible for compensation under Japan's national Relief System for Adverse Drug Reactions.
※Regarding iPS Cell-Derived Exosomes
① The iPS cell-derived exosomes used in this treatment are an unapproved drug that has not received approval under Japan's Pharmaceuticals and Medical Devices Act.
② This product is obtained through channels intended for domestic medical institutions and is used under the professional judgment of our physicians.
③ There are currently no approved pharmaceutical products in Japan with the same composition or properties as this treatment.
④ This product has not been approved in major Western countries. While research is currently being conducted in several countries, information regarding potential significant risks has not yet been fully established.
⑤ In the rare event of a serious adverse reaction, this treatment is not eligible for compensation under Japan's national Relief System for Adverse Drug Reactions.
※Regarding PRP
This treatment is provided in accordance with Japan's Act on the Safety of Regenerative Medicine (Notification Numbers: PB3250225 / PC3250242 / PC3250241).
※Regarding Autologous Adipose-Derived Stem Cells
This treatment is provided in accordance with Japan's Act on the Safety of Regenerative Medicine (Notification Numbers: PB3250224 / PB3250226 / PB3250279 / PB3250305).
Price list
Mesogun（U225）
▶︎ Initial consultation fee
￥3,300
▶︎ Follow-up consultation fee
￥2,200
|
Mesogun (U225) — Full Face |
1session 3sessions 6sessions |
￥96,800 ￥261,360 ￥493,680 |
|
|
Mesogun (U225) — Full Face |
1session 3sessions 6sessions |
￥228,000 ￥615,600 ￥1,162,800 |
|
|
Mesogun (U225) — Full Face |
1session 3sessions |
￥286,000 ￥772,200 |
|
|
Mesogun (U225) — AGA / FAGA / Scalp Care |
1session 3sessions |
￥96,800 ￥261,360 |
|
|
Mesogun (U225) — AGA / FAGA / Scalp Care |
1session 3sessions |
￥258,000 ￥696,600 |
|
|
Mesogun (U225) — AGA / FAGA / Scalp Care |
1session 3sessions |
￥286,000 ￥772,200 |