About
Mesogun（U225）
Also known as a next-generation skin booster injection, the Mesogun (U225) may help tighten pores, soften fine lines, and improve overall skin firmness and radiance. When the fine needles are introduced into the skin, they activate the skin's natural healing response — stimulating the production of collagen and elastin.
This may help refine skin texture and may support overall improvement in skin quality.
This may help refine skin texture and may support overall improvement in skin quality.
Mesogun（U225）'s Benefits
Benefits
Benefits
01
Up to 10,000 Shots in a Single Session
The Mesogun is a medical device developed in France, designed to deliver active ingredients directly into the skin.
Administering approximately 7 shots per second, a single session can achieve up to approximately 10,000 injections.
Administering approximately 7 shots per second, a single session can achieve up to approximately 10,000 injections.
02
Achieve precise, targeted skin booster injections
It is effective for improving skin texture, pores, and fine lines, and by adjusting the needle depth, injections can also be performed around the eyes.
Using ultra-fine needles, the injection speed is fast while minimizing pain.
Using ultra-fine needles, the injection speed is fast while minimizing pain.
03
Choose Your Active Ingredient
At our clinic, we offer a selection of treatment agents including PRP, iPS Cell-Derived Exosomes, and Umbilical Cord-Derived Stem Cell Secretome.
Mesogun（U225） Expected effects
Expected effects
Expected effects
Skin Quality Improvement
- Helping reduce the appearance of fine lines
- Supporting overall skin quality improvement
- Helping improve acne-prone skin
- Sagging reduction
- Helping tighten and minimize pores
Hair Growth Support
- Promotes hair growth and regrowth
Treatment Agents Offered at Ginza YR Clinic for the Mesogun (U225)
Our treatment
Our treatment
At our clinic, we offer three treatment options using the Mesogun (U225), which can be tailored to care goals.
Treatment
01
iPS Cell-Derived Exosome
Uses high-purity, highly active exosomes derived from iPS (induced pluripotent stem) cells. With superior regenerative and signaling capabilities, they strongly support the repair of skin and hair follicle cells. They help enhance skin firmness and elasticity, while also maintaining hair resilience and volume. Recommended for those seeking advanced regenerative care.
Treatment
02
Umbilical Cord-Derived Stem Cell Secretome
Formulated with enhanced levels of key active components such as EGF, ANG2, FGF2, HGF, and CD63. Some components are increased by up to eight times, with overall active ingredient levels reaching approximately ten times higher, efficiently supporting regeneration and repair. It works not only on the skin but also on the scalp, promoting a healthy skin and scalp environment.
Treatment
03
PRP Skin Regeneration Therapy
Utilizes PRP (platelet-rich plasma) extracted from the patient’s own blood to stimulate the skin’s natural regenerative ability. Growth factors promote skin repair, helping improve spots, wrinkles, and fine lines, while restoring firmness, hydration, and overall skin health. Recommended for those beginning to notice signs of aging.
Treatment
01
iPS Cell-Derived Exosome
Uses high-purity, highly active exosomes derived from iPS (induced pluripotent stem) cells. With superior regenerative and signaling capabilities, they strongly support the repair of skin and hair follicle cells. They help enhance skin firmness and elasticity, while also maintaining hair resilience and volume. Recommended for those seeking advanced regenerative care.
Treatment
02
Umbilical Cord-Derived Stem Cell Secretome
Formulated with enhanced levels of key active components such as EGF, ANG2, FGF2, HGF, and CD63. Some components are increased by up to eight times, with overall active ingredient levels reaching approximately ten times higher, efficiently supporting regeneration and repair. It works not only on the skin but also on the scalp, promoting a healthy skin and scalp environment.
Treatment
03
PRP Skin Regeneration Therapy
Utilizes PRP (platelet-rich plasma) extracted from the patient’s own blood to stimulate the skin’s natural regenerative ability. Growth factors promote skin repair, helping improve spots, wrinkles, and fine lines, while restoring firmness, hydration, and overall skin health. Recommended for those beginning to notice signs of aging.
Recommended for these concerns
Recommended
Recommended
You want to improve skin laxity and restore firmness and radiance
You are starting to notice fine lines or dryness
You want to tighten visibly enlarged pores
You want to improve the appearance of acne scarring
You want to support a healthier scalp environment and overall hair condition
Treatment overview
Treatment overview
Treatment overview
Mesogun（U225）
Duration
30 minutes to approximately 1 hour
Treatment Interval
Treatments every 4 to 6 weeks are used as a general guideline.
Downtime
In many cases, recovery is said to take a few hours to approximately one day.
※Makeup may be permitted on the day of treatment. Bathing is allowed on the day, but please avoid the treated area. For 24 hours after the procedure, please avoid vigorous exercise and saunas, and take sufficient sun protection measures. For several days after treatment, please also refrain from using highly irritating skincare products or performing facial massage.
Side Effects
Redness and swelling may occur on the day of treatment, but in many cases are said to settle within a few hours to approximately 3 days. In rare cases, bruising may occur, which is generally said to improve within approximately one week.
※The degree of effects and side effects may vary between individuals. Please consult with our physicians for a thorough explanation before considering treatment.
Price list
Price list
Price list
Mesogun（U225）
▶︎ Initial consultation fee
￥3,300
▶︎ Follow-up consultation fee
￥2,200
Mesogun (U225) — Full Face | 1session 3sessions 6sessions | ￥96,800 ￥261,360 ￥493,680 | |
Mesogun (U225) — Full Face | 1session 3sessions 6sessions | ￥228,000 ￥615,600 ￥1,162,800 | |
Mesogun (U225) — Full Face | 1session 3sessions | ￥286,000 ￥772,200 | |
Mesogun (U225) — AGA / FAGA / Scalp Care | 1session 3sessions | ￥96,800 ￥261,360 | |
Mesogun (U225) — AGA / FAGA / Scalp Care | 1session 3sessions | ￥258,000 ￥696,600 | |
Mesogun (U225) — AGA / FAGA / Scalp Care | 1session 3sessions | ￥286,000 ￥772,200 |