A Ginza clinic providing knee joint regenerative medicine and regenerative aesthetics

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About

iPS Cell-Derived Exosome Infusion

Our bodies are constantly working to repair themselves. Day by day, cells sustain damage from injury, fatigue, stress, and the natural process of aging. In youth, cells communicate rapidly — sending signals that say "let's repair this" — but it is said that as we age, that communication gradually weakens and the response slows.

iPS Cell-Derived Exosome Therapy is a form of regenerative medicine that aims to support repair by harnessing this very ability of cells to communicate. The exosomes used in this treatment are extracted and purified from cells cultured from human fat or bone marrow tissue. By supplying exosomes from outside the body, it is considered that this may help deliver "repair and regeneration signals" to cells, potentially supporting their natural function.

Among the available options, iPS Exosome Therapy — derived from iPS cells (induced pluripotent stem cells) — is attracting attention as an emerging approach in regenerative medicine. iPS cells are cells that have undergone initialisation (reprogramming) through a specialised scientific process. The exosomes obtained from these cells are of high purity, and it is considered that they may contribute to supporting cellular repair and regeneration.※Results may vary between individuals.※ Please consult with our physicians for a thorough explanation before considering treatment.
iPS Cell-Derived Exosome Infusion's Benefits
Benefits
01
Addressing a Wide Range of Symptoms
iPS Exosome Therapy is hoped to offer an approach to a broad range of symptoms associated with aging and stress, including joint discomfort, loss of skin firmness, and chronic fatigue.
02
Potential to Support Cellular Repair and Regeneration
iPS cell-derived exosomes are considered to potentially support the repair and regeneration of cells whose function has declined due to aging.

The exosomes produced from there consistently deliver a high level of repair effectiveness.
03
Flexible Administration Options
iPS Exosomes may offer certain benefits when administered on their own in some cases. At our clinic, we also propose treatment plans that may incorporate combination therapies based on each patient's symptoms and goals.

Our physicians will explain the treatment direction based on clinical evaluation and test results, guided by scientific evidence.※Results may vary between individuals.
iPS Cell-Derived Exosome Infusion Expected effects
Expected effects
Skin & Regenerative Benefits
  • Supporting the regeneration of skin cells
  • Helping improve skin texture and firmness
  • Helping reduce the appearance of wrinkles and sagging
  • Supporting hair regeneration
Joint Support
  • Helping address pain in the knees, shoulders, and hip joints
  • Helping improve symptoms associated with osteoarthritis
  • Supporting recovery from sports-related joint injuries
Cognitive Function Support
  • Supporting a sense of mental youthfulness and clarity
  • Your head feels clear and refreshed.
  • Helping improve mental sharpness and concentration
  • Supporting overall brain health
Energy & Vitality Support
  • Helping reduce feelings of fatigue
  • Supporting cellular vitality
  • Helping regulate whole-body metabolism
The iPS Exosomes Used at YR Clinic
Our treatment
At YR Clinic, we use exosomes derived from iPS cells — not mesenchymal stem cells (MSC). This is a next-generation regenerative medicine approach that aims to support repair and regeneration without transplanting cells directly.
Point 01
High Purity, High Concentration
iPS Exosomes
Through the removal of impurities and waste matter, combined with concentration processing, we achieve approximately 20 billion particles per vial. This may offer greater efficacy compared to standard products in some cases.
Point 02
Pharmaceutical-Grade Quality Control
Manufactured at a facility licensed for the processing of specified cell products, our exosomes meet inspection standards equivalent to those of pharmaceutical manufacturing plants, in compliance with national safety standards.
Point 03
High Purity iPS Cell-Derived Exosomes
Source cells used are regenerative medicine-grade iPS cells from a woman in her 20s. The exosomes obtained from these initialised (reprogrammed) cells are of high purity, and are expected to contribute to supporting cellular repair and regeneration.
※iPS cell-derived exosomes are research-use reagents. Please ensure you receive a thorough explanation from our physicians regarding clinical effects and safety, and that you are fully satisfied before proceeding with treatment. Results may vary between individuals.
Point 01
High Purity, High Concentration
iPS Exosomes
Through the removal of impurities and waste matter, combined with concentration processing, we achieve approximately 20 billion particles per vial. This may offer greater efficacy compared to standard products in some cases.
Point 02
Pharmaceutical-Grade Quality Control
Manufactured at a facility licensed for the processing of specified cell products, our exosomes meet inspection standards equivalent to those of pharmaceutical manufacturing plants, in compliance with national safety standards.
Point 03
High Purity iPS Cell-Derived Exosomes
Source cells used are regenerative medicine-grade iPS cells from a woman in her 20s. The exosomes obtained from these initialised (reprogrammed) cells are of high purity, and are expected to contribute to supporting cellular repair and regeneration.
※iPS cell-derived exosomes are research-use reagents. Please ensure you receive a thorough explanation from our physicians regarding clinical effects and safety, and that you are fully satisfied before proceeding with treatment. Results may vary between individuals.
Recommended for these concerns
Recommended

Those who want to maintain a youthful state from within the body

Those concerned about chronic fatigue or a decline in recovery ability

Those worried about loss of skin firmness, radiance, and elasticity

Those interested in care through regenerative medicine

Treatment overview
Treatment overview
iPS Cell-Derived Exosome Infusion
InfusionDuration
・iPS Cell-Derived Exosome IV Infusion:
approximately 1 hour
・iPS Exosome Local Injection:
approximately 30 minutes (add approximately 30 minutes if anesthesia is required)
※Treatment time may vary depending on the patient's body weight and treatment objectives.Side Effects
Side Effects
Mild pain or swelling at the injection site may occur, but in many cases is said to improve within a few days. Temporary sensations of warmth or fatigue may rarely be experienced, and these are generally said to settle within approximately 1 to 2 days in most cases. Should you have any concerns about your symptoms, please do not hesitate to contact our clinic.
※The degree of effects and side effects may vary between individuals. Please consult with our physicians for a thorough explanation before considering treatment.
Price list
Price list
iPS Cell-Derived Exosome Infusion
▶︎ Initial consultation fee
¥3,300
▶︎ Follow-up consultation fee
¥2,200

2ml

6ml

12ml

1session

3sessions

6sessions

¥198,000

¥534,600

¥1,009,800

At GINZA YR CLINIC, we help you achieve your ideal image!
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