About
Autologous Adipose-Derived Stem Cell Therapy (ADSC Therapy)At our clinic, fat tissue is collected from the patient after the initial consultation and blood tests, and the necessary stem cells are cultured. Once the cultivation process is complete, the stem cells are returned to the treatment area and used for conditions such as arthritis, skin damage, and autoimmune diseases. This treatment is expected to have broader applications for many other diseases in the future.
The human body is composed of more than 60 trillion cells, classified into approximately 200 to 300 different types. Among them are special cells that possess the ability to proliferate and are involved in the maintenance and repair of tissues. These are called “stem cells.”
01
Multipotency
Stem cells possess the ability to differentiate into various cell types, including skin cells and nerve cells. By taking the place of damaged or non-functioning cells, they are considered to support the body’s natural recovery.
02
Self-Renewal
Through self-renewal, stem cells are believed to play a role in replenishing the cells needed for repairing damaged tissue. The application of this property in the management of chronic conditions is also being advanced.
Stem Cell Therapy
Principles and Effects on the Body
Utilization of Mesenchymal Stem Cells
Stem cell therapy is aimed at supporting the body’s natural healing functions, with applications for various diseases and injuries being explored. In particular, the use of mesenchymal stem cells is attracting attention.
What Are Mesenchymal Stem Cells？
Mesenchymal stem cells are tissue stem cells harvested from adipose tissue, bone marrow, umbilical cord, and more. They naturally exist in the human body and possess abilities similar to pluripotent stem cells, capable of differentiating into various cell types.
Therapeutic Applications of Mesenchymal Stem Cells
The application of these stem cells to the repair and regeneration of tissues whose function has declined due to damage or aging is being advanced. It is also considered that they may contribute to the recovery of damaged sites and surrounding cells through the release of growth factors.
Why Choose Mesenchymal Stem Cells
Mesenchymal stem cells can be collected from adipose tissue through a relatively straightforward procedure. As cells derived from the patient’s own body, the risk of rejection is considered to be low, and this is one of the features that may help minimize the burden on the patient. Additionally, due to their high proliferative capacity, it is said to be relatively easy to ensure a stable supply of the cells needed for treatment.
Wide applicability
01
Joint Pain & Osteoarthritis Treatment
: Healthy Knee Joint: A joint that moves smoothly thanks to cartilage.
Structure: Smooth and uniform, with appropriate thickness and elasticity.
Function: Enables smooth joint movement and absorbs shock.
Blood flow: Low blood supply; nutrients obtained from synovial fluid.
Cells: Healthy chondrocytes that properly secrete cartilage matrix.
OsteoarthritisWhen cartilage is damaged, joint movement may deteriorate, and inflammation and pain can occur.
Structure: The surface may become rough, and the development of cracks and damage can lead to reduced thickness and elasticity in some cases.
Function: Joint movement may become less smooth, and shock absorption capacity can decrease.
Blood flow: Deterioration of blood flow may lead to a reduction in the tissue’s natural repair capacity.
Cells: Chondrocytes may decrease, and cartilage matrix secretion can become insufficient.
変形性関節炎の治療課題
変形性関節炎の治療には、損傷した軟骨の修復が必要ですが、関節内の血管が少なく、血流が悪いため、自然修復が難しいとされています。さらに、関節周囲の滑膜幹細胞は修復力が不十分なため、根本的な治療は困難と言えます。
Treatment Challenges for Osteoarthritis
Mesenchymal stem cells harvested from autologous adipose tissue are cultured and injected into the joint, with the aim of improving the affected area.
Stem Cell Therapy
Regenerative Involvement
Stem cells are believed to potentially differentiate into chondrocytes, which may promote cartilage repair.
Anti-inflammatory Effect
By secreting substances that suppress inflammation, they may contribute to the reduction of pain and swelling.
Growth Factor Secretion
Through the release of growth factors, they are considered to potentially support cartilage regeneration and repair.
Influence on Blood Flow
It is said that they may indirectly improve blood flow within the joint, potentially supporting repair function.
Improve osteoarthritis.
02
Chronic Pain Treatment
Chronic pain, as defined by the International Association for the Study of Pain (IASP), refers to pain that persists beyond the expected healing time, or pain associated with progressive non-cancerous conditions.
The 3 Main Causes of Chronic Pain
01
Disease-related pain: Includes pain associated with conditions such as rheumatoid arthritis, diabetes, and cancer.
02
Neuropathic pain: Nerve damage caused by infections such as shingles or trauma may trigger pain in some cases.
03
Psychogenic pain: Psychological factors such as stress may influence pain regulation functions in the brain, and it is considered that this may trigger pain in some cases.
How Does Stem Cell Therapy Work for Chronic Pain？
Stem Cell Therapy
Anti-Inflammatory Effects
Healing Ability
Relieve symptoms of chronic pain.
03
Applications in Skin & Hair Growth
Aging and UV exposure can cause the skin to lose firmness and elasticity, leading to wrinkles, sagging, and uneven pigmentation. At the same time, an imbalanced scalp environment and weakened hair follicle function can result in thinning hair and hair loss. These concerns are generally thought to worsen with age, chronic stress, and hormonal changes.
Age-related skin changes
How Does Stem Cell Therapy Support Skin & Hair Growth？
Stem cell therapy is being explored as a way to address age-related skin changes and support hair regrowth
by working directly on skin tissue and the scalp environment.
Stem Cell Therapy
Cell Repair & Regeneration
Targets fibroblasts and hair follicle cells
Anti-Inflammatory Support
Releases anti-inflammatory substances to help restore a healthy local environment
Growth Factor Secretion
Promotes the regeneration of skin tissue and hair follicles
Improve symptoms of arteriosclerosis.
※Results may vary from person to person.
Benefits
Seeks Out and Repairs Damaged Sites
Assists Repair of Nearby Areas
Endocrine Effect
Expected effects
- Treatment for conditions such as dementia, Alzheimer’s disease, and cerebral infarction
- Seeking treatment for knee osteoarthritis
- Improvement of chronic pain
- Interested in treatment combined with blood purification therapy
- Prevention of lifestyle-related diseases (arteriosclerosis)
- Prevention of menopausal symptoms and age-related changes
- Improvement and prevention of diabetes, liver disorders, and immune-related diseases
Recommended
Seeking treatment for conditions such as dementia, Alzheimer’s disease, and cerebral infarction
Improvement of chronic pain
Want to prevent and improve menopausal symptoms and lifestyle-related diseases
Those seeking treatment for knee osteoarthritis
Improvement and prevention of diseases such as diabetes, liver disorders, and immune-related diseases
Those interested in treatment combined with blood purification therapy
Treatment overview
A treatment plan will be developed in consultation with the doctor according to the patient’s symptoms and goals.
Injections should be administered at intervals of at least one month. Treatment once every 2 to 3 months is recommended.
-Intravenous Infusion Therapy：
Treatments can be administered at intervals as short as one month.
Ongoing infusion therapy every 2 to 3 months is recommended.
※Treatment effects and post-treatment side effects may vary from person to person.
Price list
Autologous Adipose-Derived Stem Cell Therapy — IV Drip | 200 million cells / session | 1session 3sessions 6sessions 8sessions 10sessions | ￥3,190,000 ￥8,804,400 ￥16,269,000 ￥20,416,000 ￥24,563,000 |
Adipose-Derived Stem Cell Therapy | 200 million cells / session | 1session 3sessions 6sessions | ￥1,880,000 ￥5,358,000 ￥10,377,600 |