Director, GINZA YR CLINIC

Junya Higuchi, M.D., Ph.D.

Hello, I'm Junya Higuchi, Director of GINZA YR CLINIC. After gaining broad clinical experience as a physician, I also engaged in basic research as a research doctor.
At GINZA YR CLINIC, we aim to provide care based on the latest knowledge while staying close to your concerns. Please feel free to consult us.

Director

Physician / Ph.D. (The University of Tokyo)

(Specialty) Orthopedics / Regenerative Medicine

Career

Graduated from the University of Tsukuba, School of Medicine

Completed initial clinical training at St. Mary's Hospital

Senior Resident, Department of Orthopedic Surgery, Kanto Rosai Hospital

Staff Physician, Department of Orthopedic Surgery, Toshiba Hospital

Staff Physician, Department of Orthopedic & Spine Surgery, The University of Tokyo Hospital

Staff Physician, Department of Orthopedic Surgery, JCHO Yugawara Hospital

Chief Physician, Department of Orthopedic Surgery, Yaizu City Hospital

Completed Graduate School, Graduate School of Medicine, The University of Tokyo

Assistant Professor, Department of Orthopedic Surgery, Teikyo University Mizonokuchi Hospital

Director, GINZA YR CLINIC

Professional Societies

Japanese Society for Regenerative Medicine

Japanese Orthopaedic Association

Japanese Society for Surgery of the Foot

Japanese Society for Knee Surgery and Related Research

Japanese Society of Orthopaedic Sports Medicine

Japanese Society for Joint Diseases

Publications

Peer-reviewed papers (English)

1.Higuchi J, Yamagami R, Matsumoto T, Terao T, Inoue K, Tsuji S, Maenohara Y, Matsuzaki T, Chijimatsu R, Omata Y, Yano F, Tanaka S, Saito T. Associations of clinical outcomes and MRI findings in intra-articular administration of autologous adipose-derived stem cells for knee osteoarthritis. Regen Ther. 2020 May 25;14:332-340.
2.Higuchi J, Matsumoto T, Kasai T, Takeda R, Iidaka T, Horii C, Oka H, Muraki S, Hashizume H, Yamada H, Yoshida M, Nakamura K, Tanaka S, Yoshimura N. Relationship between medial partite hallux sesamoid and hallux valgus in the general population. Foot Ankle Surg. 2023 Dec;29(8):621-626.
3.Yasui T, Higuchi J, Kasai T, Yamada A, Kobata T, Hasebe K, Hara M. Association of Preoperative Depression Score With Outcomes of Transfibular Total Ankle Arthroplasty. J Foot Ankle Surg. 2023 Sep-Oct;62(5):807-811.
4.Matsumoto T, Higuchi J, Maenohara Y, Chang SH, Iidaka T, Horii C, Oka H, Muraki S, Hashizume H, Yamada H, Yoshida M, Nakamura K, Tanaka S, Yoshimura N. The discrepancy between radiographically-assessed and self-recognized hallux valgus in a large population-based cohort. BMC Musculoskelet Disord. 2022 Jan 4;23(1):31.
5.Nagata K, Hojo H, Chang SH, Okada H, Yano F, Chijimatsu R, Omata Y, Mori D, Makii Y, Kawata M, Kaneko T, Iwanaga Y, Nakamoto H, Maenohara Y, Tachibana N, Ishikura H, Higuchi J, Taniguchi Y, Ohba S, Chung UI, Tanaka S, Saito T. Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development. Nat Commun. 2022 Oct 19;13(1):6187.
6.Chijimatsu R, Miwa S, Okamura G, Miyahara J, Tachibana N, Ishikura H, Higuchi J, Maenohara Y, Tsuji S, Sameshima S, Takagi K, Nakazato K, Kawaguchi K, Yamagami R, Inui H, Taketomi S, Tanaka S, Saito T. Correction to: Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human. Stem Cell Res Ther. 2021 Aug 26;12(1):479.
7.Chijimatsu R, Miwa S, Okamura G, Miyahara J, Tachibana N, Ishikura H, Higuchi J, Maenohara Y, Tsuji S, Sameshima S, Takagi K, Nakazato K, Kawaguchi K, Yamagami R, Inui H, Taketomi S, Tanaka S, Saito T. Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human. Stem Cell Res Ther. 2021 Jul 15;12(1):405.
8.Kawaguchi K, Michishita K, Manabe T, Akasaka Y, Arakawa T, Higuchi J. Mucoid degeneration of the cruciate ligaments in osteoarthritis under primary total knee arthroplasty. Asia Pac J Sports Med Arthrosc Rehabil Technol. 2018 Jan 5;12:1-4.
9.Kawaguchi K, Michishita K, Manabe T, Akasaka Y, Higuchi J. Comparison of an Accelerometer-Based Portable Navigation System, Patient-Specific Instrumentation, and Conventional Instrumentation for Femoral Alignment in Total Knee Arthroplasty. Knee Surg Relat Res. 2017 Dec 1;29(4):269-275.
10.Oichi T, Chikuda H, Morikawa T, Mori H, Kitamura D, Higuchi J, Taniguchi Y, Matsubayashi Y, Oshima Y, Tanaka S. Concurrent spinal schwannoma and meningioma mimicking a single cervical dumbbell-shaped tumor: case report. J Neurosurg Spine. 2015 Dec;23(6):784-7.

Presentations

1.Junya Higuchi, Taku Saito, et al. Mechanisms by which adipose-derived stem cells regulate osteoarthritis pathology. Cartilage Metabolism Society, 2022.
2.Junya Higuchi, Taku Saito, et al. Mechanisms by which adipose-derived stem cells regulate osteoarthritis pathology. Tokyo Bone and Joint Forum, 2021.
3.J. Higuchi, T. Saito, et al. Molecular mechanisms underlying adipose-derived stem cell therapy for osteoarthritis. ASBMR 2021 Annual Meeting, 2021.
4.Junya Higuchi, Taku Saito, et al. Mechanisms by which adipose-derived stem cells regulate osteoarthritis pathology. Bone Metabolism Society, 2021.
5.Junya Higuchi, Taku Saito, et al. Clinical outcomes of adipose-derived stem cell therapy for knee osteoarthritis and MRI findings related to treatment response. Japanese Society for Regenerative Medicine, 2020.
6.Junya Higuchi, Tetsuro Yasui, et al. A case of rheumatoid arthritis that developed as monoarthritis of the ankle with a mass and required differential diagnosis. Japanese Society for Joint Diseases, 2023.
7.Junya Higuchi, Tetsuro Yasui, et al. Outcomes of lateral-approach total ankle arthroplasty and their association with preoperative depression scores. Japanese Society for Surgery of the Foot, 2022.
8.Junya Higuchi, Takumi Matsumoto, et al. Relationship between medial partite hallux sesamoid and hallux valgus in a general population cohort. 46th Annual Meeting of the Japanese Society for Surgery of the Foot, 2021.
9.Junya Higuchi, Takumi Matsumoto, et al. Relationship between medial partite hallux sesamoid and hallux valgus: findings from the large-scale ROAD Study cohort. 93rd Annual Meeting of the Japanese Orthopaedic Association, 2020.
10.Junya Higuchi, Shuji Taketomi, et al. Association between footprint analysis and ankle sprain in male soccer players, UTSSI Sports Injury Prevention Project. Japanese Orthopaedic Society of Sports Medicine, 2019.
12.Junya Higuchi, Takumi Matsumoto, et al. A case of ankle arthrodesis for a massive bone defect using the Cup and Cone Reamer Technique with allogeneic femoral head bone grafting. Japanese Society for Surgery of the Foot, 2016.
13.Junya Higuchi, Tetsuro Yasui, et al. Four cases of peroneal tendon dislocation treated by pseudo-pouch closure using JuggerKnot soft anchors. Japanese Society for Surgery of the Foot, 2015.
14.Junya Higuchi, Hirotaka Chikuda, et al. A case of L1/2 intradural disc herniation. Kanto Society of Orthopaedic and Traumatology, 2015.

Doctor Profile

After initial training, I learned diagnosis and general medical management including emergency care, and then joined the Department of Orthopaedic Surgery at the University of Tokyo. At affiliated hospitals, I gained extensive experience in outpatient and surgical treatments for joint disorders, spinal disorders, trauma, and sports orthopedics.

At the University of Tokyo, I engaged in research on mesenchymal stem cells and obtained my doctorate through a study on the molecular mechanisms underlying adipose-derived stem cell therapy for knee osteoarthritis.

Currently, I provide optimal treatments for patients with a focus on regenerative medicine using stem cells.

A Ginza clinic providing knee joint regenerative medicine and regenerative aesthetics